Analytical Data
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基因名
CEACAM21
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简介
CEA21/CEACAM21, a carcinoembryonic antigen (CEA)-related cell adhesion molecule, is expressed on granulocytes. CEACAM21 is also a biological candidate gene for schizophrenia and type I diabetes, with SNPs consistently associated with the disease. CEACAM21 Protein, Human (HEK293, His) is the recombinant human-derived CEACAM21 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
rHuCarcinoembryonic antigen-related cell adhesion molecule 21/CEACAM21, His; Carcinoembryonic antigen-related cell adhesion molecule 21; CEACAM21
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3KPI0-1
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表达区间
W35-G240
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氨基酸序列
WLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYTLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHMLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLG
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蛋白长度
Extracellular Domain
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CEACAM21 (Carcinoembryonic Antigen-related Cell Adhesion Molecule 21) is a member of the CEACAM family, which plays significant roles in cell adhesion, immune response, and various biological processes. This protein is primarily expressed in the human gastrointestinal tract and has been implicated in several pathological conditions, including cancer and inflammatory diseases. The study of CEACAM21 has garnered attention due to its potential as a biomarker for disease diagnosis and prognosis, as well as its role in tumor progression and metastasis. Recombination technologies enable the production of CEACAM21 in various systems, allowing researchers to investigate its structural and functional properties. Understanding the molecular mechanisms of CEACAM21 may provide insights into therapeutic targets and strategies for treatment, particularly in cancers where CEACAM proteins are aberrantly expressed. Characterization of this recombinant protein facilitates the exploration of its interactions with other cellular components, paving the way for future research into its biological functions and therapeutic potential.
