Analytical Data
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基因名
CEACAM7
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简介
CEAM7/CEACAM7 belongs to the class of carcinoembryonic antigen (CEA) proteins, a cell surface glycoprotein. CEACAM7 is dysregulated in hyperplastic colorectal polyps and early adenomas and may serve as a potential early diagnostic and/or prognostic marker for pancreatic cancer (PanCa) or pancreatic ductal adenocarcinoma (PDAC). CEACAM7 Protein, Human (HEK293, His) is the recombinant human-derived CEACAM7 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
rHuCarcinoembryonic antigen-related cell adhesion molecule 7/CEACAM7, His; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7; Carcinoembryonic Antigen CGM2; CEACAM7; CGM2
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
AAI21133.1
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表达区间
T36-F142
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蛋白长度
Partial
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分子量
20-30 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CEACAM7 (Carcinoembryonic Antigen-related Cell Adhesion Molecule 7) is a member of the CEACAM family, which plays a significant role in cell adhesion and immune response modulation. Recent studies have highlighted its potential involvement in various physiological and pathological processes, including cancer progression, immune evasion, and pathogen interaction. CEACAM7 is predominantly expressed in epithelial tissues, and alterations in its expression have been linked to tumorigenesis, particularly in colorectal cancers. Research into recombinant CEACAM7 proteins aims to elucidate their functional roles in cell signaling, immune responses, and interactions with pathogens. Furthermore, understanding the structural and biochemical properties of CEACAM7 can provide insights into its mechanism of action and its potential as a therapeutic target. Recombinant forms of CEACAM7 can be utilized in various experimental setups, including binding assays, functional assays, and potential vaccine development, facilitating a deeper comprehension of its roles in human health and disease. Through these investigations, CEACAM7 may emerge as a promising biomarker or therapeutic candidate in oncology and immunology. Thus, the study of CEACAM7 recombinant proteins is pivotal for advancing our knowledge of cell adhesion molecules and their impact on disease processes.
