Analytical Data
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基因名
WNT16
- Application
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBV4
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表达区间
Asn30~Lys365
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分子量
70kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WNT16 is a member of the WNT gene family, which plays a crucial role in various cellular processes including cell proliferation, differentiation, and embryonic development through the Wnt signaling pathway. The interest in WNT16 has grown due to its potential implications in bone biology and diseases such as osteoporosis and certain types of cancer. Research indicates that WNT16 may contribute to bone density regulation and influencing the activity of osteoblasts and osteoclasts, making it a target for therapeutic interventions aimed at metabolic bone diseases. Its involvement in tumorigenesis has also been explored, particularly in the context of breast and colorectal cancers, where aberrations in WNT signaling pathways can lead to malignancy. The study of recombinant WNT16 protein allows researchers to investigate its biological functions and explore its potential as a biomarker or therapeutic agent. This research is particularly relevant in the context of developing new strategies for bone regeneration and cancer treatment. As such, ongoing studies focus on the production, characterization, and functional analysis of recombinant WNT16 protein to elucidate its roles in health and disease, contributing to a deeper understanding of WNT signaling dynamics and its therapeutic potentials.
