Analytical Data
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Gene name
RAB37
- Application
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Alternative Names
Ras-related protein Rab-37
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96AX2
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Expression Region
Ser19~Cys220
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Molecular Weight
26kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB37 is a member of the RAB family of small GTPases, which are critical regulators of intracellular vesicle trafficking. Considered to play an essential role in various cellular processes, including exocytosis and endocytosis, RAB37 has gained attention in recent years due to its involvement in neurodegenerative diseases and cancer. Studies have shown that RAB37 is expressed in various tissues, particularly in the nervous system, where it may be linked to neuronal signaling and synaptic function. The polymorphic nature of RAB37 suggests that variations in its expression or function could contribute to the pathophysiology of diseases like Alzheimer’s and certain types of tumors. Moreover, emerging evidence indicates that RAB37 may interact with other key proteins involved in vesicle transport, further underscoring its potential significance in maintaining cellular homeostasis. As researchers aim to unravel the intricate mechanisms behind RAB37's function and regulation, the development of recombinant RAB37 proteins has become pivotal for in vitro studies. Such studies enable the exploration of RAB37's biochemical properties, interactions, and its role in disease mechanisms, paving the way for potential therapeutic strategies targeting this GTPase. Understanding RAB37's function and its implications in health and disease will enhance our knowledge of cellular transport processes and may ultimately lead to novel approaches in treating RAB37-related disorders.
