Analytical Data
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Gene name
CST6
- Application
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Alternative Names
Cystatin E/M
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15828
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Expression Region
Arg29~Met149
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Molecular Weight
16kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CST6, or Cystatin M/E, is a member of the cystatin superfamily of cysteine protease inhibitors, and it plays a pivotal role in regulating proteolytic activity within various biological contexts. Research into CST6 has gained momentum due to its involvement in several critical physiological processes, including tissue remodeling, inflammation, and cancer progression. Notably, CST6 has been identified as a tumor suppressor in various cancer types, indicating its potential role in inhibiting cancer cell invasion and metastasis. Aberrant expression of CST6 has been associated with poor prognosis in certain malignancies, making it a target of interest for therapeutic intervention. Studies have shown that CST6 can modulate the tumor microenvironment by influencing the activity of specific proteases, thereby affecting extracellular matrix composition and immune cell infiltration. Furthermore, the functional characterization of CST6 has revealed its potential in maintaining skin homeostasis and its involvement in various dermatological conditions. Given these insights, ongoing research is focused on elucidating the molecular mechanisms underpinning CST6's regulatory roles and evaluating its potential as a biomarker and therapeutic target in oncology and other related fields. Understanding the full spectrum of CST6's functions could provide valuable insights into novel treatment strategies aimed at enhancing patient outcomes in cancer and beyond.
