Analytical Data
-
基因名
HINT2
- Application
-
别名
HIT-17kDa; PKCI-1-related HIT protein
-
种属
Mouse
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9D0S9
-
表达区间
Ile55~Gly163
-
分子量
16kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HINT2 (Histidine Triad Nucleotide-Binding Protein 2) is a member of the histidine triad (HIT) superfamily, which is known for its role in various cellular functions, including nucleotide binding and hydrolysis. Research has increasingly focused on HINT2 due to its involvement in critical biological processes and potential implications in diseases. It is expressed in multiple tissues, including the brain and heart, and has been implicated in mitochondrial function, apoptosis, and oxidative stress response. Notably, alterations in HINT2 expression or function have been associated with neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, highlighting its potential role in neuroprotection and cellular resilience. Additionally, HINT2 has garnered interest as a potential biomarker for various conditions, making it a target for therapeutic intervention. The recombinant expression and characterization of HINT2 protein have become pivotal in understanding its mechanistic role in cellular pathways, aiding in the identification of structures and interactions essential for its function. Ongoing studies aim to elucidate the structure-function relationship of HINT2, providing insights into its regulatory roles and potential exploitation in biomedicine.
