Analytical Data
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Gene name
HINT2
- Application
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Alternative Names
HIT-17kDa; PKCI-1-related HIT protein
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9D0S9
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Expression Region
Ile55~Gly163
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Molecular Weight
16kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HINT2 (Histidine Triad Nucleotide-Binding Protein 2) is a member of the histidine triad (HIT) superfamily, which is known for its role in various cellular functions, including nucleotide binding and hydrolysis. Research has increasingly focused on HINT2 due to its involvement in critical biological processes and potential implications in diseases. It is expressed in multiple tissues, including the brain and heart, and has been implicated in mitochondrial function, apoptosis, and oxidative stress response. Notably, alterations in HINT2 expression or function have been associated with neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, highlighting its potential role in neuroprotection and cellular resilience. Additionally, HINT2 has garnered interest as a potential biomarker for various conditions, making it a target for therapeutic intervention. The recombinant expression and characterization of HINT2 protein have become pivotal in understanding its mechanistic role in cellular pathways, aiding in the identification of structures and interactions essential for its function. Ongoing studies aim to elucidate the structure-function relationship of HINT2, providing insights into its regulatory roles and potential exploitation in biomedicine.
