Analytical Data
-
Gene name
GPR78
- Application
-
Species
Human
-
Source
E. coli
-
Tag
N- His & GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96P69
-
Expression Region
Val271~His363
-
Molecular Weight
42kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR78, also known as the Glucosylation-Dependent Receptor 78, is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in various physiological processes, including cell signaling, immune response, and metabolism. Studies have shown that GPR78 is involved in the regulation of glucose homeostasis and has potential implications in metabolic disorders such as obesity and diabetes. This receptor participates in the endoplasmic reticulum stress response and is implicated in the pathological mechanisms of several diseases, including cancer and neurodegenerative disorders. The exploration of GPR78 recombinant proteins has garnered significant interest due to their potential as therapeutic targets and tools for understanding GPCR signaling pathways. By producing and characterizing recombinant GPR78, researchers aim to elucidate its structural and functional properties, enhance drug discovery efforts, and develop novel therapeutics that can modulate its activity effectively. Experimental studies focusing on GPR78 recombinant proteins can provide insights into the receptor's ligand binding, activation mechanisms, and downstream signaling pathways, paving the way for innovative approaches to treat GPR78-related diseases and conditions. As a result, the research on GPR78 recombinant proteins not only contributes to the foundational knowledge of GPCR biology but also holds promise for developing targeted therapies that address the growing prevalence of metabolic and neurodegenerative diseases.
