Analytical Data
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基因名
NOLC1
- Application
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别名
P130; NOPP130; NOPP140; NS5ATP13; Nucleolar Phosphoprotein p130; 140 kDa nucleolar phosphoprotein; Hepatitis C virus NS5A-transactivated protein 13
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14978
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表达区间
Thr384~Lys587
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NOLC1, or nucleolar and coiled-body phosphoprotein 1, is a key protein involved in various cellular processes, including ribosome biogenesis and nucleolar function. Its role in the assembly and function of the nucleolus, a crucial organelle for ribosomal RNA synthesis and processing, highlights its importance in cellular homeostasis and stress responses. Research has shown that NOLC1 is implicated in several diseases, including cancer, where its expression levels often correlate with tumor progression and patient prognosis. Given the protein's essential functions and its potential as a biomarker or therapeutic target, recombinant NOLC1 has gained attention in the scientific community. Studies focusing on the characterization of recombinant NOLC1 allow for a deeper understanding of its structural and functional properties. This research is crucial for elucidating the molecular mechanisms underlying its role in normal physiology and disease states. Furthermore, exploring the interactions of NOLC1 with other nucleolar components may provide insights into the regulatory networks governing ribosome biogenesis. As a result, recombinant forms of NOLC1 can serve as valuable tools for both basic research and potential clinical applications, paving the way for novel strategies in cancer therapeutics and diagnostics.
