Cat: IPD-X39106

Recombinant Human Nesp1 Protein,His

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Analytical Data

  • Gene name

    Nesp1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SYNE1; C6orf98; 8B; MYNE1; CPG2; SCAR8; ARCA1; Enaptin; Myocyte nuclear envelope protein 1; Nuclear envelope spectrin repeat protein 1; Synaptic nuclear envelope protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8NF91

  • Expression Region

    Lys30~Pro283

  • Molecular Weight

    36kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Nesp1, a protein encoded by the Neuropeptide S (NPS) gene, has garnered significant attention in the fields of molecular biology and pharmacology due to its role in various physiological processes. Initial studies have suggested that Nesp1 is involved in neurogenesis, the modulation of anxiety and stress responses, and the regulation of metabolism. Its unique structure and the signaling pathways it engages have led researchers to explore its potential therapeutic applications, particularly in treating neurological disorders and obesity. The recombinant production of Nesp1 has become a vital area of investigation, as it facilitates the detailed study of the protein's function and interaction with other biomolecules. Techniques such as recombinant DNA technology allow for the generation of Nesp1 in host cells, leading to high yields and purity essential for functional assays. Understanding the detailed mechanisms of Nesp1 can provide insights into its broader implications in health and disease, paving the way for novel interventions targeting neuropeptide signaling pathways. Moreover, the exploration of Nesp1’s roles could enhance our comprehension of complex behaviors linked to anxiety and stress, ultimately contributing to the development of new pharmacological strategies aimed at improving mental health outcomes. Overall, research into Nesp1 recombinant proteins serves as a promising avenue for advancing not only basic scientific knowledge but also practical applications in medicine.

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