Analytical Data
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Gene name
DCDC2
- Application
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Alternative Names
DCDC2A; RU2; RU2S
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5DU00
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Expression Region
Met1~Ser240
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DCDC2, or doublecortin domain containing 2, is a protein that plays a crucial role in brain development and neurogenesis. It has garnered interest in the field of neuroscience due to its potential implications in cortical malformations and neurodevelopmental disorders. Mutations or dysregulation of the DCDC2 gene have been linked to conditions such as developmental dyslexia and other cognitive impairments, presenting a pivotal area for research. The protein is believed to be involved in cellular processes such as microtubule stabilization and neuronal migration, which are essential for proper brain architecture. Consequently, understanding the structure and function of DCDC2, along with the mechanisms through which it contributes to neuronal organization, is critical for elucidating its role in normal brain function and its associations with various neurological conditions. Researchers are increasingly focusing on the recombination and expression of DCDC2 to study its functional properties and interactions at the molecular level. This research aims to provide insights that could pave the way for therapeutic strategies targeting DCDC2-related pathways, ultimately advancing our understanding of neurodevelopmental disorders and potential interventions.
