Analytical Data
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Gene name
PCDHb15
- Application
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y5E8
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Expression Region
Val35~Leu347
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Molecular Weight
38kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PCDHb15, a member of the protocadherin family, plays a crucial role in neural development and synaptic functions. It is particularly associated with neuronal adhesion processes and is believed to have implications in the formation and maintenance of synapses in the central nervous system. Research has indicated that mutations in PCDHb15 may be linked to various neurodevelopmental disorders, highlighting its significance in understanding the molecular mechanisms underlying these conditions. The recombinant expression of PCDHb15 protein has emerged as a critical tool for studying its structural properties and functional roles in cellular contexts. By producing and purifying this protein, researchers aim to elucidate its interactions with other cellular components and its impact on neural connectivity. Moreover, generating recombinant PCDHb15 could facilitate the development of therapeutic strategies targeting related neurological disorders. Investigating the biophysical properties and pathways regulated by PCDHb15 through its recombinant form can also provide insights into the complex signaling networks involved in brain development and function. Thus, the study of PCDHb15 recombinant protein is pivotal not only for basic neuroscience research but also for potential clinical applications.
