Analytical Data
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Gene name
PPP1R3
- Application
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Alternative Names
PPP1R3A; PP1G; RG1; Glycogen And Sarcoplasmic Reticulum Binding Subunit,Skeletal Muscle; Protein phosphatase 1 glycogen-associated regulatory subunit
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
D3ZM60
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Expression Region
Met1~Cys293
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Molecular Weight
35kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP1R3, or Protein Phosphatase 1 Regulatory Subunit 3, plays a crucial role in regulating protein phosphatase 1 (PP1), which is a serine/threonine phosphatase involved in various cellular processes, including cell division, glycogen metabolism, and muscle contraction. Dysregulation of PPP1R3 has been implicated in several diseases, including diabetes, cancer, and neurodegenerative disorders, highlighting its potential as a therapeutic target. Research into recombinant PPP1R3 protein serves not only to elucidate its structure and function but also to explore its interactions with other cellular components. Facilitating the production of PPP1R3 in a recombinant system allows scientists to study its biochemical properties in detail and assess its role in signaling pathways that are vital for cell health and function. Moreover, understanding how PPP1R3 modulates PP1 activity could lead to novel strategies for the treatment of related diseases by manipulating this regulatory pathway. Thus, the study of recombinant PPP1R3 contributes significantly to the broader understanding of cellular regulation and potential therapeutic interventions.
