Analytical Data
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基因名
ABCA6
- Application
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别名
ABC-A6
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8K441
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表达区间
Val1398~Lys1616
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分子量
28kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ABCA6 (ATP-binding cassette sub-family A member 6) is a lipid transport protein that belongs to the ATP-binding cassette (ABC) transporter family. It is primarily expressed in human tissues, including the brain, liver, and heart, suggesting its potential role in lipid metabolism and cellular homeostasis. Recent studies have indicated that ABCA6 may be involved in various biological processes such as cholesterol efflux, inflammation, and cellular detoxification. Its dysregulation has also been linked to several diseases, including cardiovascular diseases and neurodegenerative disorders. The investigation of recombinant ABCA6 protein has gained attention as it provides insights into its structural and functional properties, which are crucial for understanding its role in health and disease. By producing ABCA6 in a recombinant system, researchers can explore its substrate specificity, interaction with lipids, and involvement in cellular signaling pathways. This research not only enhances our understanding of ABCA6's biological functions but also paves the way for potential therapeutic strategies targeting ABCA6-related pathways in various pathological conditions. Understanding the intricacies of ABCA6 function may yield novel insights into lipid-related disorders and contribute to the development of innovative treatments aimed at ameliorating these conditions. As the field advances, the study of ABCA6 reaffirms the significance of lipid transporters in maintaining cellular integrity and their implication in disease mechanisms.
