Analytical Data
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基因名
TNPO2
- Application
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别名
IPO3; KPNB2B; TRN2; Importin 3; Karyopherin Beta 2b
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14787
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表达区间
Leu17~Leu248
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TNPO2 (Transportin 2) is a member of the karyopherin family, which plays a crucial role in nucleocytoplasmic transport, particularly in the import of proteins containing nuclear localization signals. Recent studies have indicated that TNPO2 is involved in several important cellular processes, including cell proliferation, differentiation, and response to stress. Its role in viral infections, particularly in the importation of viral proteins into the nucleus, has garnered significant attention in virology research. Moreover, TNPO2 has been implicated in various diseases, including cancer, where its overexpression has been associated with tumor progression and poor prognosis. This has sparked interest in the development of TNPO2-targeted therapeutic strategies. The recombinant expression of TNPO2 protein in various systems, such as bacteria or mammalian cells, facilitates the study of its structure-function relationship and interaction with other cellular proteins. Understanding TNPO2's mechanism of action can provide insights into its potential as a biomarker or therapeutic target. Given the increasing recognition of its biological significance, ongoing research aims to elucidate the precise roles of TNPO2 in cellular homeostasis and disease development, thereby paving the way for innovative interventions in TNPO2-related pathologies.












