Analytical Data
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Gene name
FGF13
- Application
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Alternative Names
FHF2; Fibroblast Growth Factor Homologous Factor 2
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9ERW3
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Expression Region
Met1~Thr192
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Molecular Weight
24kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fibroblast growth factor 13 (FGF13) is a member of the fibroblast growth factor family, known for its role in various biological processes, including cell growth, differentiation, and tissue repair. Unlike classical FGFs that primarily function through receptor-mediated pathways, FGF13 primarily acts in the intracellular domain, particularly in the context of cardiac and neuronal tissues. Its involvement in cellular signaling and ion channel regulation suggests potential implications in cardiac arrhythmias and neurodegenerative diseases. Recent studies have highlighted the significance of FGF13 in modulating ion channels, such as sodium channels, thereby playing a critical role in neuronal excitability and cardiac function. The interest in FGF13 has surged due to its potential as a therapeutic target in disorders where ion channel dysfunction is implicated. Moreover, recombinant FGF13 protein opens avenues for detailed structural and functional studies, allowing researchers to elucidate its mechanisms of action, facilitate drug development, and explore its role in pathophysiological conditions. The production of recombinant FGF13 involves the use of various expression systems, ensuring proper folding and activity, which are crucial for its functional studies. Understanding the properties and interactions of FGF13 at a molecular level could provide insights into its biological significance and pave the way for novel therapeutic strategies.
