Analytical Data
-
Gene name
AXIN2
- Application
-
Alternative Names
Axil; Conductin; Axin Related Protein; Axin-like protein
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y2T1
-
Expression Region
Pro350~Lys631
-
Molecular Weight
40kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AXIN2, a member of the Axin family, plays a crucial role in the Wnt signaling pathway, which is vital for various cellular processes, including cell proliferation, differentiation, and tumorigenesis. Dysregulation of AXIN2 has been implicated in several cancers, making it an important target for therapeutic interventions. The study of AXIN2 recombinant proteins has gained traction, as these proteins can provide insights into the molecular interactions and functional mechanisms within the Wnt signaling pathway. By producing and purifying AXIN2 recombinant proteins in suitable expression systems, researchers aim to investigate their structural properties, binding affinities with other signaling proteins, and potential regulatory roles. The ability to manipulate and analyze these proteins allows for a deeper understanding of how AXIN2 contributes to cell signaling and its implications in cancer biology. Furthermore, AXIN2's association with various diseases underscores the importance of ongoing research in this area, as it may lead to novel strategies for cancer treatment and improved biomarkers for diagnostic purposes. Overall, the exploration of AXIN2 recombinant proteins stands at the intersection of molecular biology and therapeutic development, reflecting the broader significance of this protein in health and disease.
