Analytical Data
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基因名
AXIN2
- Application
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别名
Axil; Conductin; Axin Related Protein; Axin-like protein
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2T1
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表达区间
Pro350~Lys631
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AXIN2, a member of the Axin family, plays a crucial role in the Wnt signaling pathway, which is vital for various cellular processes, including cell proliferation, differentiation, and tumorigenesis. Dysregulation of AXIN2 has been implicated in several cancers, making it an important target for therapeutic interventions. The study of AXIN2 recombinant proteins has gained traction, as these proteins can provide insights into the molecular interactions and functional mechanisms within the Wnt signaling pathway. By producing and purifying AXIN2 recombinant proteins in suitable expression systems, researchers aim to investigate their structural properties, binding affinities with other signaling proteins, and potential regulatory roles. The ability to manipulate and analyze these proteins allows for a deeper understanding of how AXIN2 contributes to cell signaling and its implications in cancer biology. Furthermore, AXIN2's association with various diseases underscores the importance of ongoing research in this area, as it may lead to novel strategies for cancer treatment and improved biomarkers for diagnostic purposes. Overall, the exploration of AXIN2 recombinant proteins stands at the intersection of molecular biology and therapeutic development, reflecting the broader significance of this protein in health and disease.
