Analytical Data
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Gene name
IFITM1
- Application
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Alternative Names
Dispanin subfamily A member 2a ;DSPA2aInterferon-induced protein 17Interferon-inducible protein 9-27Leu-13 antigen; CD225
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P13164
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Expression Region
1-36AA
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IFITM1 (Interferon-Inducible Transmembrane Protein 1) is a significant membrane protein known for its role in the immune response, particularly in enhancing resistance against viral infections. It is part of a larger family of IFITM proteins that are induced by interferon, a key component of the antiviral immune response. Research has indicated that IFITM1 restricts the entry of various enveloped viruses, including influenza, HIV, and Zika virus, by altering the properties of the host cell membrane. This has led to increased interest in IFITM1 as a potential therapeutic target for antiviral strategies. Moreover, studies have shown that IFITM1 is also involved in regulating cellular processes beyond immune responses, including cell proliferation and differentiation. Understanding the structure-function relationship of IFITM1 through the development of recombinant proteins can provide insights into its molecular mechanisms and aid in the design of novel antiviral therapies. The generation of IFITM1 recombinant proteins for structural and functional analysis is crucial for unraveling its role in virus-host interactions and its potential applications in disease management.
