Analytical Data
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基因名
HMMR
- Application
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别名
CD168; RHAMM; IHABP; RHAMM; Intracellular hyaluronic acid-binding protein
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75330
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表达区间
Asn577~Lys724
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分子量
21kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HMMR, or Hyaluronan-Mediated Motility Receptor, is a significant protein involved in various cellular processes, particularly in cell motility, proliferation, and signaling pathways. Its interaction with hyaluronic acid plays a crucial role in embryonic development, tissue repair, and tumor progression. Research has increasingly focused on HMMR due to its association with cancer metastasis and poor prognosis in various malignancies. The overexpression of HMMR has been linked to enhanced migration and invasion of cancer cells, making it a potential target for therapeutic interventions. Furthermore, HMMR's role in modulating the tumor microenvironment and influencing immune responses has garnered attention in the study of cancer immunology. The generation and characterization of recombinant HMMR proteins have become essential for understanding its functional mechanisms, interactions with other cellular components, and potential therapeutic applications. Overall, the exploration of HMMR provides valuable insights into its contributions to both normal physiological processes and pathological conditions, particularly in oncology.
