Analytical Data
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Gene name
C14orf166
- Application
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Alternative Names
CLE7 homolog
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y224
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Expression Region
1-244aa
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Molecular Weight
55.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C14orf166, also known as LGR5, is a gene located on chromosome 14, which encodes a protein involved in several critical biological processes, including cell proliferation, differentiation, and tissue regeneration. Research indicates that C14orf166 plays a significant role in stem cell maintenance and renewal, particularly in the context of various cancers and developmental disorders. The investigation of C14orf166 recombinant protein has gained momentum due to its potential implications in regenerative medicine and oncology. Studies have revealed that this protein is implicated in key signaling pathways, such as Wnt and Notch, which are essential for maintaining the balance between cell growth and apoptosis. Furthermore, dysregulation of C14orf166 expression has been associated with tumorigenesis, making it a potential biomarker for cancer diagnosis and prognosis, as well as a target for therapeutic interventions. The production and characterization of C14orf166 recombinant protein can provide valuable insights into its functional roles and mechanisms, facilitating the development of novel treatment strategies. This research avenue holds promise for uncovering new therapeutic targets and advancing our understanding of the molecular underpinnings of diseases linked to C14orf166 dysregulation.
