Cat: IPD-X26436

Recombinant Human MT-RNR1 Protein,His & GST

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Analytical Data

  • 基因名

    MT-RNR1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Mitochondrial-derived peptide MOTS-c; Mitochondrial open reading frame of the 12S rRNA-c; MT-RNR1; Homo sapiens; Human; DNA-binding

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His;N-GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    A0A0C5B5G6

  • 表达区间

    R2-R16

  • 蛋白长度

    Full Length of Mature Protein

  • 分子量

    29.5 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MT-RNR1, or mitochondrial ribosomal RNA 1, plays a crucial role in the synthesis of mitochondrial proteins, which are essential for cellular respiration and energy production. Research into MT-RNR1 has gained momentum due to its involvement in various human diseases, particularly those affecting mitochondrial function, such as certain neurodegenerative disorders and metabolic syndromes. Mutations in the MT-RNR1 gene have been linked to altered mitochondrial function, resulting in impaired energy metabolism and increased oxidative stress. In addition, this gene has garnered attention in the context of pharmacogenomics, as its variations may influence individual responses to specific antibiotics, particularly aminoglycosides. Understanding the structure and function of MT-RNR1, along with the pathways it regulates, is critical for developing targeted therapeutic strategies and improving treatment outcomes for patients with mitochondrial dysfunction. The study of MT-RNR1 recombinant proteins not only provides insights into the fundamental mechanisms of mitochondrial biology but also aids in the exploration of novel approaches for diagnosing and treating diseases associated with mitochondrial anomalies. Thus, ongoing research into MT-RNR1 and its associated pathways holds significant promise for advancing our understanding of mitochondrial health and its broader implications for human health.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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