Analytical Data
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Gene name
EGR3
- Application
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Alternative Names
PILOT; Zinc Finger Protein Pilot
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q06889
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Expression Region
Cys98~Ala363
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Molecular Weight
40kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EGR3 (Early Growth Response 3) is a pivotal transcription factor involved in various cellular processes, including growth, differentiation, and response to environmental stimuli. As a member of the EGR family, EGR3 is characterized by its zinc finger domains that facilitate DNA binding and regulation of gene expression. Research has increasingly focused on EGR3 due to its role in neuronal function, immunological responses, and its potential involvement in various diseases, including cancer and neurodegenerative disorders. The study of recombinant EGR3 protein provides valuable insights into its structural properties, functional mechanisms, and interactions with other cellular factors. By generating and purifying EGR3 in a recombinant form, scientists can examine its biochemical characteristics, explore its role in transcriptional regulation, and assess the impact of specific mutations on its activity. Moreover, understanding the signaling pathways mediated by EGR3 and its target genes can unveil therapeutic targets for diseases associated with dysregulated EGR3 expression. This growing body of research highlights the importance of recombinant EGR3 protein as a tool for dissecting its biological functions and paving the way for potential medical applications.
