Analytical Data
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基因名
CD320
- Application
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别名
8D6; 8D6A; CD320 Antigen; TCblR; FDC-signaling molecule 8D6; Transcobalamin receptor
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NPF0
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表达区间
Ser36~Tyr229
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD320 is a receptor protein primarily known for its role in the metabolism of vitamin B12, playing a crucial part in cellular uptake and utilization of this essential vitamin. Research indicates that CD320 facilitates the transport of vitamin B12 across the cell membrane, thereby influencing various physiological functions, including DNA synthesis and the maintenance of neurological health. The exploration of CD320 and its recombinant protein form has gained increasing attention due to its potential implications in clinical nutrition, particularly in conditions characterized by vitamin B12 deficiency. Furthermore, understanding the structural and functional characteristics of CD320 can provide insights into its regulatory mechanisms in cellular processes. Studies have also highlighted the receptor's involvement in immune responses and inflammation, indicating that recombinant CD320 could have therapeutic applications in various diseases. The recombinant form of CD320 can be utilized in research settings to investigate its binding affinity to different forms of vitamin B12 and other ligands, aiding in the development of targeted interventions for metabolic disorders. Therefore, ongoing research into CD320's structure and functions not only enhances our understanding of vitamin B12 metabolism but also holds promise for novel therapeutic strategies to combat related health issues.
