Analytical Data
-
基因名
TRH
- Application
-
别名
TRF; Thyrotropin-Releasing Factor; Thyroliberin; Protirelin; Pro-tirelin; Prothyroliberin; TSH-releasing factor
-
种属
Human
-
表达系统
E. coli
-
标签
N- His & GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P20396
-
表达区间
Gln227~Pro229*10
-
分子量
38/28/25kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Thyrotropin-releasing hormone (TRH) is a tripeptide hormone produced in the hypothalamus that plays a crucial role in the regulation of the thyroid axis by stimulating the release of thyroid-stimulating hormone (TSH) from the pituitary gland. The study of recombinant TRH proteins has gained significant interest due to their potential applications in both basic research and therapeutic settings. Recombinant TRH can serve as a valuable tool for investigating the mechanisms underlying the hypothalamic-pituitary-thyroid (HPT) axis and its associated disorders, such as hypothyroidism and hyperthyroidism. Additionally, the production of TRH in a recombinant form allows for better control over its purity and dosage, making it suitable for use in experimental models and potential drug development. Advances in biotechnology, including techniques such as gene cloning and protein expression systems, have enabled the successful production of TRH and its analogs, facilitating studies on their physiological effects and interactions with specific receptors. Furthermore, researchers are exploring the role of TRH beyond thyroid regulation, including its involvement in neuroendocrine functions and possible implications in metabolic disorders. Overall, the research on recombinant TRH proteins holds promise for enhancing our understanding of endocrine regulation and developing novel therapeutic strategies for related diseases.
