Analytical Data
-
Gene name
SH3GLB1
- Application
-
Alternative Names
Bax-interacting factor 1
-
Species
Human
-
Source
E. coli
-
Tag
N- GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y371
-
Expression Region
1-365aa
-
Molecular Weight
67.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SH3GLB1, also known as SH3-domain-containing GRB2-like protein 1, is a crucial player in cellular processes such as endocytosis, membrane trafficking, and actin cytoskeleton remodeling. This protein contains a Src homology 3 (SH3) domain, suggesting its involvement in protein-protein interactions that regulate various signaling pathways. Research on SH3GLB1 has gained momentum due to its potential implications in several diseases, including cancer and neurodegenerative disorders. Its role in the regulation of vesicle formation and endosomal machinery has made it a focus for understanding the mechanisms of intracellular transport and signal transduction. Investigating the structure and function of SH3GLB1, especially through the development of recombinant proteins, allows scientists to elucidate its specific interactions and downstream effects in cellular physiology. Furthermore, the ability of SH3GLB1 to modulate cellular responses to external stimuli underscores its importance in maintaining cellular homeostasis. The ongoing exploration of SH3GLB1's function may provide insights into therapeutic targets, enhancing our understanding of disease mechanisms and opening new avenues for intervention. Overall, the study of SH3GLB1 and its recombinant forms serves as a critical step toward deciphering the complexities of cellular dynamics and their implications in health and disease.
