Cat: IPD-X38218

Recombinant Human SPLUNC2 Protein(HEK293),His

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Analytical Data

  • 基因名

    SPLUNC2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    BPIFA2; PSP; C20orf70; BPI fold-containing family A member 2; Parotid secretory protein

  • 种属

    Human

  • 表达系统

    HEK293

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96DR5

  • 表达区间

    Glu19~Ile249

  • 分子量

    35kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SPLUNC2 (Short palate, lung, and nasal epithelium clone 2) is a protein primarily expressed in the respiratory and nasal epithelia, where it plays a crucial role in innate immunity and mucosal defense. It is part of the broader SPLUNC family, which is known for its involvement in maintaining airway homeostasis and regulating inflammatory responses. Recent studies have highlighted SPLUNC2's various functions, including antibacterial activity, modulation of mucin secretion, and protective roles against respiratory pathogens, suggesting its potential as a biomarker for respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Given its diverse functions and involvement in epithelial barrier integrity, researchers are increasingly focused on understanding the molecular mechanisms underlying SPLUNC2's activity. This includes examining the protein's structure-function relationship, its interactions with other biomolecules, and its regulatory pathways. The recombinant expression of SPLUNC2 can facilitate the investigation of its biological properties and therapeutic potential. By producing large quantities of the protein, researchers aim to conduct functional assays and elucidate its role in inflammation and host defense mechanisms. Additionally, SPLUNC2's potential as a therapeutic target or biomarker has drawn attention in the context of developing novel treatments for respiratory conditions, emphasizing the importance of ongoing research into this multifaceted protein. Overall, the study of SPLUNC2 not only contributes to our understanding of respiratory biology but also paves the way for innovative approaches to combat respiratory diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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