Analytical Data
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Gene name
SCG2
- Application
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Alternative Names
SN; SgII; CHGC; Chromogranin C; Secretoneurin
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Species
Human
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Source
HEK293
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P13521
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Expression Region
Gln31~Met617
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Molecular Weight
80kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SCG2 (secretagogin 2) is a calcium-binding protein that plays a critical role in neuronal and endocrine systems. Its involvement in neurotransmitter release and neuronal signaling has attracted considerable attention in recent years, as dysregulation of SCG2 has been associated with various neurological disorders, including schizophrenia and depression. The protein's ability to bind calcium ions suggests a potential role in regulating intracellular signaling pathways and exocytosis in neuroendocrine cells. Research into SCG2 primarily focuses on its structure, function, and molecular interactions, which are vital for understanding its role in the cell signaling mechanisms. Additionally, the development of recombinant SCG2 proteins has emerged as a key area of interest, as these proteins can be utilized to study SCG2's physiological roles, assess its interaction with other proteins, and explore its potential therapeutic applications. By providing a detailed understanding of SCG2 and its functionality, researchers hope to unravel the complexities of neurotransmission and identify novel targets for drug development in the treatment of neurological diseases. The production of recombinant SCG2 opens new avenues for innovative research, allowing for extensive studies on its mechanisms and the broader implications for synaptic plasticity and neurodegenerative disorders.
