Analytical Data
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Gene name
MCD
- Application
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Alternative Names
MCD; Malonyl-CoA decarboxylase, mitochondrial
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q99J39
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Expression Region
Ser190~Leu492
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Molecular Weight
37kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MCD (Malonyl-CoA decarboxylase) recombined proteins have garnered significant attention in recent years due to their essential role in lipid metabolism and energy homeostasis. As a key enzyme in the regulation of malonyl-CoA levels, MCD catalyzes the conversion of malonyl-CoA to acetyl-CoA, facilitating fatty acid oxidation and reducing lipid accumulation in tissues. Research suggests that altered MCD activity is linked to various metabolic disorders, including obesity, type 2 diabetes, and heart disease. Understanding the structure and function of MCD through recombinant protein studies can reveal insights into its regulatory mechanisms and potential therapeutic targets. Additionally, recombinant MCD proteins provide a valuable tool for investigating the enzyme's kinetics, interaction with other metabolic pathways, and the impact of post-translational modifications. This growing body of research aims to elucidate the role of MCD in metabolic diseases and explore how modulation of its activity could contribute to developing innovative treatments for metabolic syndrome.
