Analytical Data
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基因名
TM2D1
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简介
The TM2D1 protein may be involved in amyloid beta-induced apoptosis by interacting with beta-APP42, especially amyloid beta protein 42 (APP beta-APP42). This suggests a role in molecular pathways associated with amyloid-induced cell death. TM2D1 Protein, Human (HEK293, Fc) is the recombinant human-derived TM2D1 protein, expressed by HEK293 , with C-mFc labeled tag.
- Application
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别名
TM2 domain-containing protein 1; Amyloid-beta-binding protein; hBBP; BBP
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种属
Human
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表达系统
HEK293
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标签
C-mFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BX74
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表达区间
T38-G118
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蛋白长度
Partial
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分子量
45-60 kDa band in SDS-PAGE under reducing conditions.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TM2D1, a member of the transmembrane (TM) domain family, is involved in various physiological processes, including cell signaling and membrane dynamics. Its role in cellular functions has garnered interest in both basic and applied research. The protein's unique structure, characterized by multiple transmembrane domains, suggests potential interactions with membrane lipids and other membrane proteins, which are crucial for maintaining cellular integrity and communication. Studies have indicated that TM2D1 may be implicated in specific diseases, underscoring its potential as a biomarker or therapeutic target. The need for detailed understanding of TM2D1's structure-function relationship has spurred research into its biochemical properties and interactions. Current methodologies, including recombinant protein expression and purification, enable the characterization of TM2D1's functional role at the molecular level. Additionally, insights into its signaling pathways may reveal novel mechanisms underlying various pathologies, paving the way for innovative therapeutic strategies. Exploring TM2D1's biological significance and potential applications in medicine is a priority for advancing knowledge in cell biology and molecular medicine.
