Analytical Data
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Gene name
MZB1/PERP1
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简介
MZB1/PERP1 protein binds to IgM heavy and light chains and helps IgM assembly and secretion. It acts as a molecular chaperone or oxidoreductase and exhibits low oxidoreductase activity. MZB1/PERP1 Protein, Human (HEK293, His) is the recombinant human-derived MZB1/PERP1 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Marginal zone B- and B1-cell-specific protein; MEDA7; PACAP
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q8WU39-1
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Expression Region
D23-T185
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Protein Length
Partial
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Molecular Weight
19-23 kDa due to glycosylation
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MZB1/PERP1 is a novel protein that has gained attention in the field of cellular biology due to its potential roles in cell survival and apoptosis regulation. Originally identified as a gene regulated by the interferon response, MZB1/PERP1 is primarily expressed in immune tissues and has been implicated in various physiological processes. Recent studies suggest that it may function as a mediator of the endoplasmic reticulum stress response and has been linked to the modulation of apoptosis in certain cellular contexts. Understanding the mechanistic pathways involving MZB1/PERP1 could provide insights into its role in immune response and its potential implications in diseases such as cancer and autoimmune disorders. Due to its association with critical cellular functions, MZB1/PERP1 presents as a promising candidate for biomedical research, with the potential to uncover new therapeutic targets. Given the complexity of its functions, ongoing investigations are focused on elucidating the molecular interactions and regulatory networks that govern MZB1/PERP1's activities, as well as its contribution to the pathophysiology of various diseases.
