Analytical Data
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Gene name
FAM171B
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简介
FAM171B may play a role in the progression of pulmonary hypertension by stimulating immune infiltration and immune response. FAM171B promotes tumor progression by stabilizing vimentin in the cytoplasm. FAM171B is a candidate gene for a neurodegenerative disease whose molecules have not yet been characterized. FAM171B Protein, Human (HEK293, His) is the recombinant human-derived FAM171B protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Protein FAM171B; KIAA1946; NPD019
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Species
Human
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Source
HEK293
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Tag
C-6*His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
AAH60872
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Expression Region
R31-T355
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AA Sequence
RAELSRSDLSLIQQQQQQQQQQQQQQQQKQLEEAEEERTEVPGATSTLTVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWINHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHT
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Protein Length
Partial
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Molecular Weight
43-57 kDa.
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FAM171B, a member of the FAM171 gene family, has emerged as a significant research focus due to its potential roles in cellular signaling and development. This gene is implicated in various biological processes, including cell proliferation, differentiation, and apoptosis. Recent studies suggest that FAM171B may play a crucial role in the immune response and neurodevelopment, raising interest in its function and mechanisms. The need for understanding FAM171B has intensified with discoveries linking its dysregulation to several diseases, including neurodevelopmental disorders and cancers. Furthermore, the exploration of FAM171B-recombinant proteins offers promising avenues for probing its biological activity and therapeutic applications. The purification and characterization of FAM171B recombinant proteins enable researchers to investigate their structural properties and interactions with other cellular components. This research is paramount for elucidating the specific functions of FAM171B, as well as its potential as a biomarker or therapeutic target. Overall, the ongoing study of FAM171B and its recombinant forms holds significant promise for advancing our understanding of complex biological systems and developing innovative strategies for disease treatment.
