Analytical Data
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Gene name
Annexin A7/ANXA7
- Application
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Alternative Names
ANX-A7; ANX7; SNX; Synexin
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
P20073
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Expression Region
Met1~Lys309
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Molecular Weight
36kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Annexin A7 (ANXA7) is a member of the annexin protein family, which is known for its ability to bind phospholipids in a calcium-dependent manner. This protein plays a crucial role in various cellular processes, including membrane trafficking, cell signaling, and apoptosis. Research on ANXA7 has gained momentum due to its involvement in several pathological conditions, including cancer, neurodegenerative diseases, and cardiovascular disorders. Studies have shown that ANXA7 can act as a tumor suppressor, with its downregulation linked to the progression of certain cancers, such as prostate and breast cancer. Furthermore, its expression is associated with the regulation of ion channels and synaptic plasticity, making it a significant player in neuronal function. The production of recombinant ANXA7 protein has allowed for in-depth biochemical and functional studies, enabling researchers to elucidate its structure-function relationship and its interactions with other proteins. This recombinant protein serves as a valuable tool for understanding the mechanistic roles of ANXA7 in health and disease, providing insights into its potential as a therapeutic target. Overall, the investigation of ANXA7 and its recombinant forms continues to be a promising area of biomedical research aimed at uncovering new strategies for disease intervention and therapeutic development.
