Cat: IPD-X29876

Recombinant Mouse CIRBP Protein,His

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Analytical Data

  • 基因名

    CIRBP

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Cirbp; CirpCold-inducible RNA-binding protein; A18 hnRNP; Glycine-rich RNA-binding protein CIRP

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    C-6*His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P60824

  • 表达区间

    M1-E172

  • 蛋白长度

    Full Length

  • 分子量

    29 kDa, based on SDS-PAGE under reducing conditions,

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CIRBP (Cold Inducible RNA Binding Protein) is an intriguing multifunctional protein that has garnered attention in recent years due to its role in various cellular processes, particularly in response to environmental stressors such as cold temperatures and oxidative stress. It is known to modulate mRNA stability and translation, thereby influencing gene expression during stress responses. Research has shown that CIRBP plays a significant role in cellular differentiation, apoptosis, and the regulation of circadian rhythms, making it a potential candidate for studying various pathological conditions, including cancer and neurodegenerative diseases. The ability of CIRBP to act as an RNA chaperone further highlights its importance in maintaining RNA integrity and function under adverse conditions. As such, recombinant CIRBP has become a valuable tool for investigating its molecular mechanisms and interactions in vitro and in vivo. Researchers are increasingly focusing on characterizing the protein's structure and function to elucidate its roles in stress responses and its potential as a therapeutic target. The production of recombinant CIRBP allows for better understanding of its properties, paving the way for novel therapeutic strategies aimed at targeting CIRBP-related pathways in disease contexts. Moreover, the study of CIRBP's interaction with various RNA species and other cellular proteins can provide insights into the intricate regulatory networks that govern cellular homeostasis and response to stress, underscoring the significance of this protein in maintaining cellular health and function. Overall, continued research into recombinant CIRBP is essential for unlocking its multifaceted roles and therapeutic potential in health and disease.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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