Analytical Data
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Gene name
AK2
- Application
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Alternative Names
ATP-AMP transphosphorylase 2 ATP:AMP phosphotransferase Adenylate monophosphate kinase
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P54819
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Expression Region
1-239aa
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Molecular Weight
53.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Related Products
Protein Description
AK2 (adenylate kinase 2) is a crucial enzyme involved in cellular energy homeostasis, catalyzing the conversion of ATP to ADP and AMP, thus playing a vital role in maintaining the balance of adenine nucleotides in the cell. The study of recombinant AK2 protein has gained significant attention due to its involvement in various biological processes, including cellular respiration, apoptosis, and signal transduction pathways. Dysregulation of AK2 expression or function has been linked to several diseases, including cancer and mitochondrial disorders, highlighting its potential as a therapeutic target. Moreover, understanding AK2's structure-function relationships can provide insights into its catalytic mechanisms and substrate specificity. As a recombinant protein, AK2 can be produced in different expression systems, allowing for detailed biochemical characterizations, structural studies, and functional assays. This research not only aids in elucidating AK2's biological roles but also paves the way for the development of AK2-based interventions and biomarker discovery, further emphasizing its relevance in both basic and applied biomedical research.
