Analytical Data
-
Gene name
SCGB3A2
-
简介
SCGB3A2 is a secreted cytokine-like protein that interacts with pathogens (Listeria monocytogenes, Pseudomonas aeruginosa, yeast) and binds to the scavenger receptor MARCO. It strongly inhibits PLA2G1B activity and regulates lipid metabolism. SCGB3A2 Protein, Mouse (His, GST) is the recombinant mouse-derived SCGB3A2 protein, expressed by E. coli , with N-GST, N-6*His labeled tag.
- Application
-
Alternative Names
Scgb3a2; Pnsp1; Ugrp1; Secretoglobin family 3A member 2; Pneumo secretory protein 1; PnSP-1; Uteroglobin-related protein 1
-
Species
Mouse
-
Source
E. coli
-
Tag
N-GST;N-6*His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q920H1-1
-
Expression Region
L22-L139
-
Protein Length
Partial
-
Molecular Weight
43 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SCGB3A2, also known as Secretoglobin Family 3A Member 2, is a member of the secretoglobin protein family that has garnered significant attention in recent years due to its potential role in various physiological and pathological processes. Originally identified in the context of the respiratory system, SCGB3A2 is expressed in epithelial cells of the lungs and has been implicated in protecting against oxidative stress and inflammation. Research has suggested that it may play a crucial role in lung homeostasis and could be involved in the pathogenesis of pulmonary diseases, including asthma and chronic obstructive pulmonary disease (COPD). Additionally, SCGB3A2 has been found to be differentially expressed in several cancers, indicating its potential as a biomarker for tumor progression and prognosis. The recombinant production of SCGB3A2 protein facilitates the study of its structure-function relationship, offering insights into its biological activities and interactions with other biomolecules. Furthermore, understanding the mechanisms of SCGB3A2 could lead to novel therapeutic strategies targeting respiratory conditions and malignancies. As such, the investigation of SCGB3A2 recombinant protein not only enhances our comprehension of its functional roles but also opens avenues for translational applications in biomedical research.
