Analytical Data
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Gene name
C-Reactive
- Application
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Alternative Names
C-Reactive Protein; CRP; PTX1
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Species
Human
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Source
HEK293
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Tag
C-Avi;C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P02741-1
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Expression Region
Q19-P224
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Molecular Weight
80-100 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C-Reactive Protein (CRP) is a pentameric protein synthesized by the liver in response to inflammation, primarily regulated by interleukin-6 (IL-6). It serves as a crucial biomarker for various inflammatory conditions and plays a significant role in the innate immune response by binding to phosphocholine on the surface of dead or dying cells and certain bacteria, leading to the activation of complement and opsonization for phagocytosis. Over the years, extensive research has demonstrated that elevated levels of CRP are associated with various diseases, including cardiovascular disorders, infections, and autoimmune diseases. As a result, the recombinant production of CRP has garnered interest for its potential in both diagnostic applications and therapeutic interventions. Recombinant CRP can be used in studies to investigate its biological functions, interactions with other immune components, and potential effects on disease progression. Moreover, the development of recombinant CRP may contribute to improved diagnostic tools and more targeted therapies, which could enhance the management of inflammatory conditions. Understanding the structure and function of recombinant CRP is essential for its application in clinical settings, paving the way for new strategies to combat diseases characterized by chronic inflammation.
