Analytical Data
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基因名
Cardiac troponin I/Tnni3
- Application
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别名
(Cardiac troponin I)
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种属
Cat
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q863B6
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表达区间
2-210aa
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分子量
27.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MecA is a critical gene associated with methicillin resistance in Staphylococcus aureus, a major pathogen responsible for various infections worldwide. The emergence of methicillin-resistant Staphylococcus aureus (MRSA) poses significant challenges for public health due to limited treatment options and increased morbidity and mortality. Researchers have focused on understanding the mechanism of resistance conferred by the MecA gene, which encodes a penicillin-binding protein (PBP2a) that alters the bacterium's cell wall synthesis, enabling it to survive even in the presence of beta-lactam antibiotics. The recombination and expression of MecA derivatives in model systems, including bacteria and yeast, allow scientists to study the structure-function relationships of this protein, its role in antibiotic resistance, and its potential as a target for novel therapeutic interventions. Investigating the recombinant MecA protein provides insights into the molecular basis of resistance and could lead to the development of strategies to combat MRSA infections effectively. Understanding MecA's function at the molecular level is essential for advancing antibiotic therapy and enhancing our ability to manage resistant strains of Staphylococcus aureus, ultimately improving patient outcomes and public health responses.












