Analytical Data
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Gene name
Cardiac troponin I/Tnni3
- Application
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Alternative Names
(Cardiac troponin I)
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Species
Cat
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q863B6
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Expression Region
2-210aa
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Molecular Weight
27.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MecA is a critical gene associated with methicillin resistance in Staphylococcus aureus, a major pathogen responsible for various infections worldwide. The emergence of methicillin-resistant Staphylococcus aureus (MRSA) poses significant challenges for public health due to limited treatment options and increased morbidity and mortality. Researchers have focused on understanding the mechanism of resistance conferred by the MecA gene, which encodes a penicillin-binding protein (PBP2a) that alters the bacterium's cell wall synthesis, enabling it to survive even in the presence of beta-lactam antibiotics. The recombination and expression of MecA derivatives in model systems, including bacteria and yeast, allow scientists to study the structure-function relationships of this protein, its role in antibiotic resistance, and its potential as a target for novel therapeutic interventions. Investigating the recombinant MecA protein provides insights into the molecular basis of resistance and could lead to the development of strategies to combat MRSA infections effectively. Understanding MecA's function at the molecular level is essential for advancing antibiotic therapy and enhancing our ability to manage resistant strains of Staphylococcus aureus, ultimately improving patient outcomes and public health responses.
