Analytical Data
-
基因名
TMCO1
- Application
-
种属
Human
-
表达系统
E. coli Cell-free
-
标签
N-10*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UM00
-
表达区间
M1-S188
-
氨基酸序列
STMFADTLLIVFISVCTALLAEGITWVLVYRTDKYKRLKAEVEKQSKKLEKKKETITESAGRQQKKKIERQEEKLKNNNRDLSMVRMKSMFAIGFCFTALMGMFNSIFDGRVVAKLPFTPLSYIQGLSHRNLLGDDTTDCSFIFLYILCTMSIRQNIQKILGLAPSRAATKQAGGFLGPPPPSGKFS
-
蛋白长度
Partial
-
分子量
23 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMCO1, or Transmembrane and Coiled-Coil Domain 1, is a protein that has garnered attention in recent years due to its role in various cellular processes, including calcium homeostasis and cell proliferation. Initial studies have indicated that TMCO1 may function as an essential component of the endoplasmic reticulum (ER) and is involved in the regulation of Ca2+ levels within cells. Dysregulation of calcium signaling has been implicated in numerous diseases, including neurodegenerative disorders and cancer, highlighting the importance of understanding TMCO1's biological functions. Research has shown that TMCO1 is not only crucial for maintaining ER function but also plays a role in modulating stress responses within cells. Its potential involvement in pathophysiological conditions has spurred efforts to investigate the structural characteristics and functional mechanisms of TMCO1 through recombinant protein techniques. By expressing TMCO1 as a recombinant protein, scientists aim to characterize its biochemical properties, explore its interactions with other cellular components, and elucidate its precise role in disease mechanisms. This research could ultimately contribute to identifying TMCO1 as a potential therapeutic target, emphasizing its significance in both basic biology and clinical applications.
