Analytical Data
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Gene name
HDGF2
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简介
HDGF2 protein actively promotes cell proliferation by enhancing DNA synthesis. This protein plays a crucial role in promoting DNA replication, an essential process required for cell division and growth. HDGF2 Protein, Human (HEK293, His) is the recombinant human-derived HDGF2 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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Alternative Names
Hepatoma-Derived Growth Factor-Related Protein 3; HRP-3; Hepatoma-Derived Growth Factor 2; HDGF-2; HDGFRP3; HDGF2
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Species
Human
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Source
HEK293
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Tag
C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y3E1
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Expression Region
M1-T203
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AA Sequence
MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT
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Protein Length
Full Length
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Molecular Weight
30-35 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HDGF2 (Hyaluronan-binding protein with a Glucose Depletion Function 2) is a relatively understudied protein that has garnered attention for its potential roles in cellular processes such as proliferation, migration, and tumorigenesis. As a member of the HDGF family, HDGF2 is thought to be involved in the regulation of gene expression and cellular responses to environmental changes. Its binding affinity to hyaluronic acid suggests a significant role in extracellular matrix interactions and cell signaling pathways. Recent studies indicate that HDGF2 may regulate various oncogenic processes, making it a potential biomarker for certain cancers. Furthermore, the expression patterns of HDGF2 vary among different tissues and developmental stages, hinting at its functional versatility. Understanding the structure and function of HDGF2, particularly through techniques like protein recombination, is crucial for elucidating its biological roles and therapeutic potential. This research is essential not only for advancing our knowledge of HDGF2 but also for exploring its possible implications in targeted cancer therapies and regenerative medicine. As we continue to investigate the intricate functions of HDGF2, new insights may pave the way for innovative strategies to combat diseases associated with its dysregulation.
