Analytical Data
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基因名
CAMKI delta/CAMK1D
- Application
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别名
rHuCAMK1D, N-GST; Calcium/calmodulin-dependent protein kinase type 1D; CaMKI-like protein kinase; CAMK1D;
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种属
Human
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表达系统
E. coli
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标签
N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IU85-1
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表达区间
M1-K385
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氨基酸序列
MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKMARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
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蛋白长度
Full Length of Isoform-1
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分子量
60-70 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CAMK1D, also known as Ca2+/calmodulin-dependent protein kinase ID (CAMK1D), is a member of the calcium/calmodulin-dependent protein kinase (CaMK) family, which plays a crucial role in various cellular processes, including cardiac function, neuronal signaling, and cellular responses to stress. The study of CAMK1D has gained interest due to its involvement in regulating gene expression, influencing apoptosis, and contributing to synaptic plasticity. Overexpression or mutation of CAMK1D has been linked to several pathologies, including cardiovascular diseases and neurological disorders. The production of recombinant CAMK1D protein allows researchers to elucidate its specific biochemical properties, explore its interaction with calmodulin and other cellular partners, and investigate its functional effects within different signaling pathways. Additionally, the recombinant protein can be utilized in high-throughput screening to identify small molecule inhibitors that target CAMK1D, presenting potential therapeutic avenues for diseases where CAMK1D is implicated. Understanding the mechanistic roles of CAMK1D in health and disease is vital, as it may lead to the development of novel interventions that can modulate its activity for therapeutic benefits. Overall, the research surrounding CAMK1D and its recombinant forms is poised to advance our comprehension of calcium signaling and its far-reaching impacts on human health.
