Analytical Data
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Gene name
CAMKI delta/CAMK1D
- Application
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Alternative Names
rHuCAMK1D, N-GST; Calcium/calmodulin-dependent protein kinase type 1D; CaMKI-like protein kinase; CAMK1D;
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Species
Human
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Source
E. coli
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Tag
N-GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IU85-1
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Expression Region
M1-K385
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AA Sequence
MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKMARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
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Protein Length
Full Length of Isoform-1
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Molecular Weight
60-70 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CAMK1D, also known as Ca2+/calmodulin-dependent protein kinase ID (CAMK1D), is a member of the calcium/calmodulin-dependent protein kinase (CaMK) family, which plays a crucial role in various cellular processes, including cardiac function, neuronal signaling, and cellular responses to stress. The study of CAMK1D has gained interest due to its involvement in regulating gene expression, influencing apoptosis, and contributing to synaptic plasticity. Overexpression or mutation of CAMK1D has been linked to several pathologies, including cardiovascular diseases and neurological disorders. The production of recombinant CAMK1D protein allows researchers to elucidate its specific biochemical properties, explore its interaction with calmodulin and other cellular partners, and investigate its functional effects within different signaling pathways. Additionally, the recombinant protein can be utilized in high-throughput screening to identify small molecule inhibitors that target CAMK1D, presenting potential therapeutic avenues for diseases where CAMK1D is implicated. Understanding the mechanistic roles of CAMK1D in health and disease is vital, as it may lead to the development of novel interventions that can modulate its activity for therapeutic benefits. Overall, the research surrounding CAMK1D and its recombinant forms is poised to advance our comprehension of calcium signaling and its far-reaching impacts on human health.
