Analytical Data
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Gene name
IRF5
- Application
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Alternative Names
Irf5Interferon regulatory factor 5; IRF-5
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Species
Mouse
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Source
E. coli
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Tag
N-6*His;N-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P56477
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Expression Region
M1-Q497
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IRF5 (Interferon Regulatory Factor 5) is a crucial transcription factor involved in the regulation of immune responses and plays a significant role in the pathogenesis of various autoimmune diseases and infections. Research has highlighted its importance in modulating the expression of interferons and other pro-inflammatory cytokines, thereby influencing T cell differentiation and the overall inflammatory response. Due to its pivotal role in immune regulation, IRF5 has been identified as a potential therapeutic target for conditions such as systemic lupus erythematosus and other autoimmune disorders. Recombinant IRF5 protein research aims to elucidate its functional mechanisms, understand its interactions with other signaling pathways, and explore its therapeutic potential. By producing and characterizing recombinant IRF5, researchers can assess its structural and functional properties, which can lead to novel insights into immune regulation and the development of targeted treatments. Furthermore, studying IRF5's role in various diseases may uncover biomarkers for disease susceptibility and progression, contributing to personalized medicine strategies. Overall, the investigation of recombinant IRF5 is critical for advancing our understanding of immune mechanisms and offers promising avenues for innovative therapeutic approaches.
