Analytical Data
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基因名
IRF5
- Application
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别名
Irf5Interferon regulatory factor 5; IRF-5
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种属
Mouse
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表达系统
E. coli
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标签
N-6*His;N-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56477
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表达区间
M1-Q497
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IRF5 (Interferon Regulatory Factor 5) is a crucial transcription factor involved in the regulation of immune responses and plays a significant role in the pathogenesis of various autoimmune diseases and infections. Research has highlighted its importance in modulating the expression of interferons and other pro-inflammatory cytokines, thereby influencing T cell differentiation and the overall inflammatory response. Due to its pivotal role in immune regulation, IRF5 has been identified as a potential therapeutic target for conditions such as systemic lupus erythematosus and other autoimmune disorders. Recombinant IRF5 protein research aims to elucidate its functional mechanisms, understand its interactions with other signaling pathways, and explore its therapeutic potential. By producing and characterizing recombinant IRF5, researchers can assess its structural and functional properties, which can lead to novel insights into immune regulation and the development of targeted treatments. Furthermore, studying IRF5's role in various diseases may uncover biomarkers for disease susceptibility and progression, contributing to personalized medicine strategies. Overall, the investigation of recombinant IRF5 is critical for advancing our understanding of immune mechanisms and offers promising avenues for innovative therapeutic approaches.












