Analytical Data
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Gene name
FGG/Fibrinogen gamma chain
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简介
FGG (fibrinogen gamma chain) proteins cooperate with FGA and FGB to form an insoluble fibrin matrix that is critical for hemostasis and wound repair. Although FGG is not required for thrombosis, it stabilizes lesions and guides cell migration during epithelialization. FGG/Fibrinogen gamma chain Protein, Mouse (P.pastoris, Tag Free) is the recombinant mouse-derived FGG/Fibrinogen gamma chain, expressed by P. pastoris, with tag Free labeled tag. The total length of FGG/Fibrinogen gamma chain Protein, Mouse (P.pastoris, Tag Free) is 269 a.a..
- Application
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Alternative Names
Fibrinogen gamma chain; FGG; PRO2061
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Species
Mouse
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Source
P. pastoris
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8VCM7
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Expression Region
V168-V436
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The Fibrinogen gamma chain (FGG) is an essential component of the fibrinogen protein, playing a critical role in blood coagulation and wound healing. Fibrinogen itself is a soluble plasma glycoprotein that gets converted to fibrin during the clotting process, which is vital for maintaining hemostasis. Recent studies have highlighted the importance of FGG not only in coagulation but also in various pathological conditions, including cardiovascular diseases, cancer progression, and inflammation. As a result, the recombinant expression of FGG has garnered significant attention, as it offers a platform for investigating its functional properties and potential therapeutic applications. Recombinant FGG enables researchers to study the structural and functional aspects of this protein in detail, facilitating the exploration of its role in clot formation and stability. The ability to produce FGG in a controlled environment also paves the way for developing novel biomaterials for use in tissue engineering and regenerative medicine. Furthermore, understanding the variations in FGG due to genetic polymorphisms can provide insights into individual predispositions to thrombotic disorders. Consequently, the study of recombinant FGG is vital for advancing our knowledge of hemostatic mechanisms and developing targeted treatments for related diseases.
