Analytical Data
-
基因名
FBXO48
- Application
-
别名
FBXO48; FBX48F-box only protein 48
-
种属
Human
-
表达系统
E. coli
-
标签
N- His & C- Myc
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q5FWF7
-
表达区间
1-155aa
-
分子量
25.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FBXO48, a member of the F-box protein family, plays a crucial role in ubiquitination and protein degradation pathways, which are essential for regulating various cellular processes. Research has shown that FBXO48 is involved in targeting specific proteins for degradation via the proteasome, thereby maintaining cellular homeostasis and regulating the cell cycle. Dysregulation of FBXO48 has been implicated in several diseases, including cancer, where alterations in the ubiquitin-proteasome system can lead to abnormal cell proliferation and survival. Understanding the function of FBXO48 and its substrate interactions can provide insights into its biological significance and potential as a therapeutic target. Recent studies have focused on elucidating the molecular mechanisms through which FBXO48 recognizes and interacts with its substrates, as well as exploring its potential roles in different cellular contexts. The development of recombinant FBXO48 proteins allows for advanced in vitro and in vivo studies, providing a platform to investigate its structure-function relationships and the impact of post-translational modifications. As research into FBXO48 continues to evolve, it holds promise not only for enhancing our understanding of ubiquitin-mediated processes but also for identifying novel strategies in drug development for diseases related to protein misregulation.
