Analytical Data
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Gene name
Glutathione S-transferase kappa 1/GSTK1
- Application
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Alternative Names
GST-K1; GST13; HDCMD47P; Glutathione S-transferase subunit 13
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q9Y2Q3
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Expression Region
Thr7~Val222
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Molecular Weight
28kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Glutathione S-transferase kappa 1 (GSTK1) is a member of the glutathione S-transferase superfamily, which plays a crucial role in the detoxification of endogenous and exogenous compounds. Located in the mitochondria, GSTK1 is known for its ability to conjugate glutathione to various substrates, thereby facilitating their excretion and mitigating oxidative stress. Its involvement in cellular defense mechanisms against oxidative damage and toxic substances has garnered significant attention in recent research. Abnormal GSTK1 expression has been linked to various pathological conditions, including cancer, neurodegenerative diseases, and metabolic disorders. As a result, recombinant GSTK1 protein has become a focal point for studies aimed at elucidating its functional properties and potential therapeutic applications. Researchers utilize recombinant techniques to produce high yields of GSTK1 for structural and functional analyses, enhancing our understanding of its enzymatic activities and interactions with different substrates. Furthermore, investigations into GSTK1's role in drug metabolism and resistance emphasize its potential as a biomarker in personalized medicine. Understanding the mechanisms governing GSTK1 function and regulation may pave the way for novel interventions targeting diseases associated with oxidative stress and xenobiotic exposure. Overall, the study of recombinant GSTK1 is poised to contribute significantly to the fields of biochemistry, pharmacology, and medical research.
