Analytical Data
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基因名
IGFBP1
- Application
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别名
Igfbp1; Igfbp-1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1
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种属
Rat
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21743
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表达区间
26-272aa
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分子量
30.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Insulin-like growth factor binding protein 1 (IGFBP1) is a key regulator of insulin-like growth factors (IGFs), which play crucial roles in cell growth, differentiation, and metabolism. IGFBP1 modulates the availability and activity of IGFs by binding to them, thereby influencing various physiological processes, including fetal development, metabolism, and tissue repair. Research has indicated that altered levels of IGFBP1 are associated with several pathophysiological conditions, such as obesity, diabetes, and certain cancers, making it a potential biomarker and therapeutic target. The recombinant production of IGFBP1 has garnered significant interest as it allows for detailed studies on its structure-function relationships and therapeutic applications. Advances in recombinant DNA technology have enabled the efficient expression and purification of IGFBP1, facilitating investigations into its molecular interactions and biological effects. Moreover, recombinant IGFBP1 has been utilized in various in vitro and in vivo studies to explore its role in regulating IGF signaling pathways. Understanding the functional mechanisms of IGFBP1 is crucial for developing novel strategies for disease intervention and management, highlighting its significance in both basic research and clinical applications. As such, the exploration of IGFBP1 as a recombinant protein holds promise for elucidating its biological functions and therapeutic potential in metabolic and neoplastic diseases.
