Analytical Data
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基因名
14-3-3 beta
- Application
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别名
Protein kinase C inhibitor protein 1
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种属
Mouse
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9CQV8
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表达区间
1-246aa
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分子量
30.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
14-3-3 proteins are a family of highly conserved regulatory molecules that play a crucial role in various cellular processes, including signal transduction, cell cycle regulation, and apoptosis. Among these, the 14-3-3 beta isoform has garnered significant interest due to its involvement in cognitive function and neurodevelopment. Dysregulation of 14-3-3 beta has been implicated in several neurodegenerative disorders and psychiatric conditions, making it a potential therapeutic target. Research has shown that 14-3-3 beta interacts with numerous client proteins, modulating their stability and activity, which highlights its significance in maintaining cellular homeostasis. The recombinant expression of 14-3-3 beta in various cellular systems allows for detailed studies of its structure-function relationships and interaction networks. These studies contribute to our understanding of how 14-3-3 beta influences cellular signaling pathways and cellular responses to stress, which is critical for developing targeted therapies. The exploration of 14-3-3 beta in both normal physiology and disease states represents a promising avenue for advancing medical research and therapeutic interventions.
