Analytical Data
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Gene name
CPSF73
- Application
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Alternative Names
CPSF73
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKF6
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Expression Region
M1-G460
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPSF73, a subunit of the cleavage and polyadenylation specificity factor (CPSF) complex, plays a crucial role in the post-transcriptional processing of mRNA. This protein is primarily involved in the cleavage of pre-mRNA followed by polyadenylation, a process essential for the stability, transport, and translation of mRNA. Understanding the function and structure of CPSF73 is important because it can influence gene expression and cellular responses to various stimuli. Abnormalities in mRNA processing are linked to numerous diseases, including certain cancers and neurodegenerative disorders, making CPSF73 a potential target for therapeutic intervention. Recent studies utilizing recombinant CPSF73 have aimed to elucidate its mechanisms of action, interactions with other RNA-binding proteins, and its role in the regulation of gene expression. By producing and characterizing this recombinant protein, researchers hope to gain insights into the molecular basis of mRNA maturation and its implications in health and disease. This research not only advances our understanding of fundamental cellular processes but also opens avenues for the development of novel strategies in biomedicine.
