Analytical Data
-
基因名
ACY3
- Application
-
别名
rHuACY3, His; N-acyl-aromatic-L-amino acid amidohydrolase; ACY-3
-
种属
Human
-
表达系统
E. coli
-
标签
N-6*His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96HD9
-
表达区间
M1-S319
-
氨基酸序列
HHHHHHMCSLPVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLANPAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKASGQAFDFVLDLHNTTANMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQVFLYQRSGEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLAGTVHPQLQDRDFQPLQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEKFTFTVPAMPALTPAPSPAS
-
蛋白长度
Full Length
-
分子量
35 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACY3, or Aminoacylase 3, is a member of the aminoacylase family of enzymes that play a vital role in the hydrolysis of N-acylamino acids into free amino acids. Its significance is underscored by its involvement in various physiological processes, including neuronal function, metabolism, and potential pathways related to neurodegenerative diseases. Recent studies have pointed to ACY3 as a key player in regulating the levels of bioactive lipids and signaling molecules, which can influence neuroinflammation and oxidative stress responses. Additionally, genetic polymorphisms in the ACY3 gene have been associated with cognitive function and certain psychiatric disorders, making it a target of interest for therapeutic interventions. The recombinant expression of ACY3 protein allows for in-depth functional studies, enabling researchers to elucidate its catalytic mechanisms, substrate specificity, and interactions with other biomolecules. Understanding the structure-function relationship of ACY3 is crucial for developing potential applications in treating metabolic disorders and enhancing cognitive health. The exploration of ACY3 as a therapeutic target highlights the importance of protein engineering and recombinant technologies in advancing our knowledge of enzymatic functions and their implications in human health.
