Analytical Data
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基因名
PHPT1
- Application
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别名
Phosphohistidine phosphatase 1;Protein janus-A homolog
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种属
Human
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRX4
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表达区间
1-125aa
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分子量
15.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PHPT1 (Phosphate-regulating gene with homologies to Endopeptidases on the X chromosome 1) is a putative protein implicated in the regulation of phosphate metabolism, particularly in the context of various physiological and pathological conditions. Research into PHPT1 has gained attention due to its potential role in conditions such as familial hypophosphatemic rickets, where mutations in phosphate-regulating genes lead to disrupted phosphate homeostasis. Understanding the function and regulation of PHPT1 could provide insights into the pathogenesis of phosphate-related disorders as well as other metabolic conditions involving mineral metabolism. The recombinant production of PHPT1 protein is critical for biochemical assays, enabling the exploration of its enzymatic function, structural characteristics, and interactions with other molecules. Such studies may facilitate the development of therapeutic interventions targeting dysregulated phosphate metabolism, thereby addressing a range of clinical challenges related to bone health and mineral deficiencies. Additionally, elucidating the role of PHPT1 in signaling pathways may reveal broader implications for its involvement in cellular processes beyond mineral regulation, thus providing a comprehensive understanding of its biological significance.












