Cat: IPD-X24371

Recombinant Mouse Lymphocyte antigen 6E/LY6E Protein,His

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Analytical Data

  • Gene name

    Lymphocyte antigen 6E/LY6E

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RIG-E; RIGE; SCA-2; SCA2; TSA-1; Retinoic Acid Induced Gene E; Stem cell antigen 2; Thymic shared antigen 1

  • Species

    Mouse

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q64253

  • Expression Region

    Leu21~Ser101

  • Molecular Weight

    13kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Lymphocyte antigen 6E (LY6E) is a member of the LY6 gene family, which encodes glycosylphosphatidylinositol (GPI)-anchored proteins involved in immune responses. The study of LY6E has gained attention due to its role in modulating immune cell functions, particularly in lymphocytes. Research has shown that LY6E plays a critical role in influencing T cell activation, proliferation, and differentiation, thereby impacting overall immune responses. Furthermore, LY6E has been implicated in various diseases, including cancers and viral infections, where it may modulate the immune evasion mechanisms of pathogens or tumor cells. The recombinant LY6E protein serves as a valuable tool for elucidating the biological functions of this antigen and its potential therapeutic applications. By generating and characterizing the recombinant LY6E protein, researchers can explore its interactions with other immune receptors, assess its signal transduction pathways, and investigate its potential as a biomarker or therapeutic target. Overall, studying LY6E and its recombinant forms enhances our understanding of immune regulation and opens avenues for novel immunotherapeutic strategies.

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