Analytical Data
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Gene name
NLRP7
- Application
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Alternative Names
NALP7; NOD12; PYPAF3
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Species
Human
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Source
Baculovirus
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Tag
Strep;His;MBP
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8WX94-1
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Expression Region
M1-C980
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Protein Length
Full Length of Isoform-1
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NLRP7 (NOD-like receptor family pyrin domain containing 7) is an important member of the NLR family of pattern recognition receptors involved in the innate immune response. This protein plays a critical role in the detection of intracellular pathogens and the regulation of inflammation. Mutations in the NLRP7 gene have been linked to certain genetic disorders, including recurrent hydatidiform moles with a risk of gestational trophoblastic disease, highlighting its significance in reproductive health. The study of NLRP7 recombinant protein is crucial for understanding its structural and functional properties, which may provide insights into its mechanisms of action in immune response. Researchers utilize recombinant DNA technology to produce NLRP7 protein, allowing for the analysis of its interactions with other cellular components, ligands, and signaling pathways. This research not only enhances our comprehension of NLRP7's role in immune regulation but also opens avenues for therapeutic interventions in diseases associated with NLRP7 dysregulation. Understanding the molecular mechanisms of NLRP7 can pave the way for novel strategies in treating inflammatory diseases and improving reproductive outcomes. Overall, the study of NLRP7 recombinant protein represents a significant area of research with implications for immunology, reproductive biology, and translational medicine.
