Analytical Data
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基因名
NLRP7
- Application
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别名
NALP7; NOD12; PYPAF3
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种属
Human
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表达系统
Baculovirus
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标签
Strep;His;MBP
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WX94-1
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表达区间
M1-C980
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蛋白长度
Full Length of Isoform-1
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NLRP7 (NOD-like receptor family pyrin domain containing 7) is an important member of the NLR family of pattern recognition receptors involved in the innate immune response. This protein plays a critical role in the detection of intracellular pathogens and the regulation of inflammation. Mutations in the NLRP7 gene have been linked to certain genetic disorders, including recurrent hydatidiform moles with a risk of gestational trophoblastic disease, highlighting its significance in reproductive health. The study of NLRP7 recombinant protein is crucial for understanding its structural and functional properties, which may provide insights into its mechanisms of action in immune response. Researchers utilize recombinant DNA technology to produce NLRP7 protein, allowing for the analysis of its interactions with other cellular components, ligands, and signaling pathways. This research not only enhances our comprehension of NLRP7's role in immune regulation but also opens avenues for therapeutic interventions in diseases associated with NLRP7 dysregulation. Understanding the molecular mechanisms of NLRP7 can pave the way for novel strategies in treating inflammatory diseases and improving reproductive outcomes. Overall, the study of NLRP7 recombinant protein represents a significant area of research with implications for immunology, reproductive biology, and translational medicine.












